Start with 1 to 2 doses an hour, but do not use more than 5 doses an hour or more than 40 doses a day.

At first, you may have side effects like a burning feeling in your nose, runny nose, a sore throat, watering eyes, sneezing, or a cough. If you continue to use the spray regularly, these side effects should get better in a few days. Tell your doctor if any side effects do not get better.

Get your doctor's advice on how long to use the spray, and follow all directions that come with the spray very carefully. Check in with your doctor or clinic if you have any problems. Start to cut back after 6 to 8 weeks. Page 42 gives you tips about cutting back. Work toward stopping the spray in 3 months.

Check the package insert for any support programs that may be offered through the manufacturer.

Hold the inhaler between your fingers and puff on it. As you inhale or puff through the mouthpiece, notine turns into a vapor and is absorbed in your mouth and throat. The inhaler may be especially appealing to smokers who think that having something to hold and put in their mouths will be helpful when they don't have cigarettes.

Use the inhaler longer and more often at first to help control cigarette cravings. Less nicotine per puff is released when you use the inhaler compared to a cigarette. The inhaler uses nicotine cartridges that provide about 20 minutes of puffing, or about 80 deep draws or about 300 light puffs.

Your doctor my adjust the number of inhaler cartridges you use during the first few weeks. Most successful people in research studies used between 6 and 16 cartridges a day. The best effect happened with frequent continuous puffing(20 minutes). You may have side effects such as throat and mouth irritation, coughing and upset stomach. As your body adjusts to being smoke free, your doctor will either tell you to stop using the inhaler or slowly reduce its use. Do not use more than 16 cartridges each day unless directed to do so by your doctor. The recommended treatment is up to three months and if needed, a gradual reduction over the next 6-12 weeks. Total treatment should not exceed six months.

Check the package insert for any support programs that may be offered through the manufacturer.

Zyban® (sustained-released bupropion, also sold as Wellbutrin SR) is an antidepressant now approved to help smokers to quit smoking. Research has shown that Zyban® assits in smoking cessation for all kinds of smokers, even those who are not depressed. it also can prevent weight gain while patients are taking it but this effect stops after patients stop taking Zyban®.

Follow your doctor's instructions for using Zyban®. Usual dosing is to start taking Zyban® 7-14 days before your quit date in order for it to reach effective levels in your body by the time you quit.

Between 7 and 14 days before your quit date, usual dosing is to begin taking 150mg, once per day, for 3 days. The next day, begin taking 150mg, twice per day, through your quit date. You should then stay on Zyban® for 8-12 weeks. Space doses at least 8 hours apart. The calendar in Appendix A, page 46, shows an example of when to start your Zyban® and when to quit smoking. If you have trouble sleeping, take the doses earlier in the day, but no fewer than 8 hours apart.

Zyban® is most likely to be effective when used with a program that helps you to beat the addiction

Seizure is the major serious side effect, so Zyban® should not be used by anyone with a history of epilepsy or who is more likely to have a seizure (such as a prior closed head injury or history of seizures). It should be used with caution in smokers with heavy alcohol used, anorexia, or bulimia. There is no proof yet about its safety during pregnancy or breastfeeding. Fewer than 10% of patients stop the drug because of side effects. The most common side effects include trouble sleeping, agitation or anxiety, dry mouth, and headache.

Zyban® can be used alone or at the same time as nicotine replcement therapy such as nicotine patches, gum, nasal spray, or inhaler. Ask your health care provider if this may be right for you.

Check the package insert for any support programs that may be offered through the manufacturer.